教員紹介
教授 坂本 昌也
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専門分野
糖尿病・代謝・内分泌学
特に糖尿病と心血管疾患に関して。近年では大規模臨床研究にも携わっている。 -
研究テーマ
2型糖尿病患者の血糖・血圧値・脂質値の関係とその変動に関する研究。
2型糖尿病患者と心不全に関する研究 -
研究実績
【researchmap】
https://researchmap.jp/omasa0723
【代表論文】- Sakamoto M, Minamino T, Toko H, Kayama Y, Zou Y, Sano M, Takaki E, Aoyagi T, Tojo K, Tajima N et al: Upregulation of heat shock transcription factor 1 plays a critical role in adaptive cardiac hypertrophy. Circulation research 2006, 99(12):1411-1418.
- Zou Y, Zhu W, Sakamoto M, Qin Y, Akazawa H, Toko H, Mizukami M, Takeda N, Minamino T, Takano H, Nagai T, Nakai A, Komuro I .Heat shock transcription factor 1 protects cardiomyocytes from ischemia/reperfusion injury. Circulation. 2003 Dec 16;108(24):3024-30.
- Suzuki H, Kayama Y, Sakamoto M [Equal contributer], Iuchi H, Shimizu I, Yoshino T, Katoh D, Nagoshi T, Tojo K, Minamino T et al: Arachidonate 12/15-lipoxygenase-induced inflammation and oxidative stress are involved in the development of diabetic cardiomyopathy. Diabetes 2015, 64(2):618-630.
- Iuchi H, Sakamoto M [corresponding author], Matsutani D, Suzuki H, Kayama Y, Utsunomiya K, et al. Time-dependent effects of ipragliflozin on behaviour and energy homeostasis in normal and type 2 diabetic rats: continuous glucose telemetry analysis.Sci Rep 2017 ;7(1):11906.
- Sakamoto M, Nishimura R, Irako T, Tsujino D, Ando K, Utsunomiya K: Comparison of vildagliptin twice daily vs. sitagliptin once daily using continuous glucose monitoring (CGM): crossover pilot study (J-VICTORIA study). Cardiovascular diabetology 2012, 11:92.
- Sakamoto M, Suzuki H, Hayashi T, Iuchi H, Isaka T, Sakamoto N, Kayama Y, Tojo K, Yoshimura M, Utsunomiya K: Effects of candesartan in hypertensive patients with type 2 diabetes mellitus on inflammatory parameters and their relationship to pulse pressure. Cardiovascular diabetology 2012, 11:118.
- Matsutani D, Sakamoto M [Equal contributer･corresponding author], Iuchi H, Minato S, Suzuki H, Kayama Y, Takeda N, Horiuchi R, Utsunomiya K: Glycemic variability in continuous glucose monitoring is inversely associated with baroreflex sensitivity in type 2 diabetes: a preliminary report. Cardiovascular diabetology 2018, 17(1):36.
- Matsutani D, Sakamoto M [Equal contributer･corresponding author], Kayama Y, Takeda N, Horiuchi R, Utsunomiya K: Effect of canagliflozin on left ventricular diastolic function in patients with type 2 diabetes. Cardiovascular diabetology 2018, 17(1):73.
- Matsutani D, Sakamoto M [Equal contributer･corresponding author], Minato S, Kayama Y, Takeda N, Horiuchi R, Utsunomiya K: Visit-to-visit HbA1c variability is inversely related to baroreflex sensitivity independently of HbA1c value in type 2 diabetes.
Cardiovascular diabetology 2018, 17(1):100. - Sakamoto M [corresponding author], Matsutani D, Minato S, Tsujimoto Y, Kayama Y, Takeda N, Ichikawa S, Horiuchi R, Utsunomiya K, Nishikawa M: Seasonal Variations in the Achievement of Guideline Targets for HbA1c, Blood Pressure, and Cholesterol Among Patients With Type 2 Diabetes: A Nationwide Population-Based Study (ABC Study: JDDM49). Diabetes Care 2019, 42(5):816-823.
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学位・学歴
博士（医学）（東京慈恵会医科大学）
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職歴・学会
前東京慈恵会医科大学准教授、元千葉大学大学院医学研究科循環病態医科学、元東京大学大学院医学研究科循環器内科
一貫して糖尿病代謝学と循環器学の両分野に渡る研究を実施してきた。2020年4月より現職。
日本糖尿病学会認定指導医・糖尿病専門医、日本内分泌学会認定指導医・内分泌代謝科専門医、日本高血圧学会認定指導医・高血圧専門医、日本内科学会認定総合内科専門医、厚生労働省認定臨床研修指導医 -
メッセージ
糖尿病・内分泌専門医を取得しながら、研究を通して新しい発見を一緒に発信しましょう。