Hirohama D, Nishimoto M, Ayuzawa N, Kawarazaki W, Fujii W, Oba S, Shibata S, Marumo T, Fujita T: Activation of Rac1-mineralocorticoid receptor pathway contributes to renal injury in salt-loaded db/db mice. Hypertension. 2021; 78:82-93.
Takenaka T, Hasan A, Marumo T, Kobori H, Inoue T, Miyazaki T, Suzuki H, Nishiyama A, Ishii N, Hayashi M: Klotho supplementation attenuates blood pressure and albuminuria in murine model of IgA nephropathy. J Hypertens. 2021; 39:1567-1576.
Rahman A, Matsuyama M, Ebihara A, Shibayama Y, Hasan AU, Nakagami H, Suzuki F, Sun J, Kobayashi T, Hayashi H, Nakano D, Kobara H, Masaki T, Nishiyama A. Antiproliferative effects of monoclonal antibodies against (pro)renin receptor in pancreatic ductal adenocarcinoma. Mol Cancer Ther. 2020; 19(9):1844-1855. doi: 10.1158/1535-7163.
Marumo T, Hoshino J, Kawarazaki W, Nishimoto M, Ayuzawa N, Hirohama D, Yamanouchi M, Ubara Y, Okaneya T, Fujii T, Yuki K, Atsumi Y, Sato A, Arai E, Kanai Y, Shimosawa T, Fujita T: Methylation pattern of urinary DNA as a marker of kidney function decline in diabetes. BMJ Open Diabetes Res Care. 2020; 8 (1), e001501.
Hirohama D, Kawarazaki W, Nishimoto M, Ayuzawa N, Marumo T, Shibata S, Fujita T: PGI 2 analog attenuates salt-induced renal injury through the inhibition of inflammation and rac1-MR activation. Int J Mol Sci. 2020, 21, 12, 4433.
Kawarazaki W, Mizuno R, Nishimoto M, Ayuzawa N, Hirohama D, Ueda K, Kawakami-Mori F, Oba S, Marumo T, Fujita T: Salt causes aging-associated hypertension via vascular Wnt5a under Klotho deficiency. J Clin Invest. 2020; 130 (8), 4152-4166.
Ayuzawa N, Nishimoto M, Ueda K, Hirohama D, Kawarazaki W, Shimosawa T, Marumo T, Fujita T: Two mineralocorticoid-receptor-mediated mechanisms of pendrin activation in distal nephrons. J Am Soc Nephrol. 2020; 31:748-764.
Rahman A, Hasan AU, Kobori H. Melatonin in chronic kidney disease: a promising chronotherapy targeting the intrarenal renin-angiotensin system. Hypertens Res. 2019; 42(6): 920-923
Hasan AU, Rahman A, Kobori H. Interactions between Host PPARs and Gut Microbiota in Health and Disease. Int J Mol Sci. 2019; 17:20(2). pii: E387
Nishimoto M, Ohtsu H, Marumo T, Kawarazaki W, Ayuzawa N, Ueda K, Hirohama D, Kawakami-Mori F, Shibata S, Nagase M, Isshiki M, Oba S, Shimosawa T, Fujita T. Mineralocorticoid receptor blockade suppresses dietary salt-induced ACEI/ARB-resistant albuminuria in NON-diabetic hypertension: A SUB-ANALYSIS of EVALUATE STUDY. Hypertens Res. 2019; 42(4); 514-521
Hasan AU, Ohmori K, Hashimoto T, Kamitori K, Yamaguchi F, Rahman A, Tokuda M, Kobori H. PPARγ activation mitigates glucocorticoid receptor-induced excessive lipolysis in adipocytes via homeostatic crosstalk. J Cell Biochem. 2018; 119(6): 4627-4635
Rahman A, Hasan AU, Nishiyama A, Kobori H. Altered circadian timing system-mediated non-dipping pattern of blood pressure and associated cardiovascular disorders in metabolic and kidney diseases. Int J Mol Sci. 2018; 19(2). pii: E400
Watanabe A, Marumo T, Kawarazaki W, Nishimoto M, Ayuzawa N, Ueda K, Hirohama D, Tanaka T, Yagi S, Ota S, Nagae G, Aburatani H, Kumagai H, Fujita T. Aberrant DNA methylation of pregnane X receptor underlies metabolic gene alterations in the diabetic kidney. Am J Physiol Renal Physiol. 2018; 314: F551-F560
Oba S, Ayuzawa N, Nishimoto M, Kawarazaki W, Ueda K, Hirohama D, Kawakami-Mori F, Shimosawa T, Marumo T, Fujita T. Aberrant DNA methylation of Tgfb1 in diabetic kidney mesangial cells. Sci Rep. 2018; 8: 16338
Kawakami-Mori F, Nishimoto M, Reheman L, Kawarazaki W, Ayuzawa N, Ueda K, Hirohama D, Kohno D, Oba M, Shimosawa T, Marumo T, Fujita T. Aberrant DNA methylation of hypothalamic angiotensin receptor in prenatal programmed hypertension. JCI Insight. 2018; 3(21): e95625
Hirohama D, Ayuzawa N, Ueda K, Nishimoto M, Kawarazaki W, Watanabe A, Shimosawa T, Marumo T, Shibata S, Fujita T. Aldosterone is essential for angiotensin II-induced upregulation of pendrin. J Am Soc Nephrol. 2018; 29: 57-68
Murase S, Shiiya T, Higuchi H. Neuropeptide Y Y5 receptor localization in mouse central nervous system. Brain Research. 2017; 1655: 216-232
Ueda K, Nishimoto M, Hirohama D, Ayuzawa N, Kawarazaki W, Watanabe A, Shimosawa T, Loffing J, Zhang MZ, Marumo T, Fujita T. Renal dysfunction induced by kidney-specific gene deletion of Hsd11b2 as a primary cause of salt-dependent hypertension. Hypertension. 2017; 70: 111-118
Marumo T, Yagi S, Kawarazaki W, Nishimoto M, Ayuzawa N, Watanabe A, Ueda K, Hirahashi J, Hishikawa K, Sakurai H, Shiota K, Fujita T. Diabetes induces aberrant DNA methylation in the proximal tubules of the kidney. J Am Soc Nephrol. 2015; 26: 2388-2397
Mu S, Shimosawa T, Ogura S, Wang H, Uetake Y, Kawakami-Mori F, Marumo T, Yatomi Y, Geller DS, Tanaka H, Fujita T. Epigenetic modulation of the renal beta-adrenergic-WNK4 pathway in salt-sensitive hypertension. Nat Med. 2011; 17: 573-580
Ishihara Y, Ohmori K, Mizukawa M, Hasan AU, Noma T, Kohno M. Beneficial direct adipotropic actions of pitavastatin in vitro and their manifestations in obese mice. Atherosclerosis. 2010; 212(1): 131-138
Murase S, Cho C, White JM, Horwitz AF. ADAM2 promotes migration of neuroblasts in the rostral migratory stream to the olfactory bulb. European Journal of Neuroscience, 2008; 27(7): 1585-1595
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