Nishimura W, Iwasa H, Tumurkhuu M. Role of the transcription factor MAFA in the maintenance of Pancreatic β-Cells. Int J Mol Sci 2022; 23: 4478.
Tumurkhuu M, Batbuyan U, Yuzawa S, Munkhsaikhan Y, Batmunkh G, Nishimura W. A novel BICD2 mutation of a patient with Spinal Muscular Atrophy Lower Extremity Predominant 2. Intractable Rare Dis Res 2021; 10: 102-108.
Nishimura W, Takayanagi Y, Tumurkhuu M, Zhou R, Miki H, Noda Y. Effect of long-term confinement on metabolic and physiological parameters in mice. Physiol Behav 2021; 234: 113386.
Amo-Shiinoki K, Tanabe K, Hoshii Y, Matsui H, Harano R, Fukuda T, Takeuchi T, Bouchi R, Takagi T, Hatanaka M, Takeda K, Okuya S, Nishimura W, Kudo A, Tanaka S, Tanabe M, Akashi T, Yamada T, Ogawa Y, Ikeda E, Nagano H, Tanizawa Y. Islet cell dedifferentiation is a pathologic mechanism of long-standing progression of type 2 diabetes. JCI Insight 2021; 11: 143791.
Udagawa H, Hiramoto M, Kawaguchi M, Uebanso T, Ohara-Imaizumi M, Nammo T, Nishimura W, Yasuda K. Characterization of taste receptor-related G-protein α-gustducin in pancreatic β-cells. J Diabetes Investig 2020; 11: 814-822.
Nammo T, Udagawa H, Funahashi N, Kawaguchi M, Uebanso T, Hiramoto M, Nishimura W, Yasuda K. Genome-wide profiling of histone H3K27 acetylation featured fatty acid signalling in pancreatic beta cells in diet-induced obesity in mice. Diabetologia 2018; 61: 2608-2620.
Mochizuki S, Miki H, Zhou R, Kido Y, Nishimura W, Kikuchi M, Noda Y. Oxysterol-binding protein-related protein (ORP) 6 localizes to the ER and ER-plasma membrane contact sites and is involved in the turnover of PI4P in cerebellar granule neurons. Exp Cell Res 2018; 370: 601-612.
Nishimura W, Sakaue-Sawano A, Takahashi S, Miyawaki A, Yasuda K, Noda Y. Optical clearing of the pancreas for visualization of mature β-cells and vessels in mice. Islets 2018; 10: e1451282.
Iwasa H, Sarkar A, Shimizu T, Sawada T, Hossain S, Xu X, Maruyama J, Arimoto-Matsuzaki K, Withanage K, Nakagawa K, Kurihara H, Kuroyanagi H, Hata Y. UNC119 is a binding partner of tumor suppressor Ras-association domain family 6 and induces apoptosis and cell cycle arrest by MDM2 and p53. Cancer Sci 2018; 109, 2767-2780.
Ohzawa H, Miki A, Teratani T, Shiba S, Sakura Y, Nishimura W, Noda Y, Fukushima N, Fuji H, Hozumi Y, Mukai H, Yasuda Y. Usefulness of miRNA profiles for predicting pathological responses to neoadjuvant chemotherapy in patients with human epidermal growth factor receptor 2‑positive breast cancer. Oncol Lett 2017; 13: 1731-1740.
Oe S, Miki H, Nishimura W, Noda Y. Mechanism of dendritic translation and localization of brain-derived neurotrophic factor. Cell Struct Funct 2016; 41: 23-31.
Nishimura W, Kapoor A, Khattabi IE, Jin W, Yasuda K, Bonner-Weir S, Sharma A. Compensatory response by late embryonic tubular epithelium to the reduction in pancreatic progenitors. PLoS ONE 2015; 10: e0142286.
Nishimura W, Ishibashi N, Eto K, Funahashi N, Udagawa H, Miki H, Oe S, Noda Y, Yasuda K. Demethylation of the MafB promoter in a compromised β-cell model. J Mol Endocrinol 2015; 55: 31-40.
Asahara S, Etoh H, Inoue H, Teruyama K, Shibutani Y, Ihara Y, Kawada Y, Bartolome A, Hashimoto N, Matsuda T, Koyanagi-Kimura M, Kanno A, Hirota Y, Hosooka T, Nagashima K, Nishimura W, Inoue H, Matsumoto M, Higgins MJ, Yasuda K, Inagaki N, Seino S, Kasuga M, Kido Y. Paternal allelic mutation at the Kcnq1 locus reduces pancreatic β-cell mass via epigenetic modification of Cdkn1c. Proc Natl Acad Sci USA 2015; 112: 8332-8337.
Hiramoto M, Udagawa H, Watanabe A, Miyazawa K, Ishibashi N, Kawaguchi M, Uebanso T, Nishimura W, Nammo T, Yasuda K. Allele comparative analysis of type 2 diabetes-associated SNPs identifies allele-specific DNA-binding proteins for the KCNQ1 locus. Int J Mol Med 2015; 36: 222-230.
Nishimura W, Takahashi S, Yasuda K. MafA is critical for maintenance of the mature beta cell phenotype in mice. Diabetologia 2015; 58: 566-574.
Ohzawa H, Miki A, Hozumi Y, Miyazaki C, Sagara Y, Tanaka Y, Shiba S, Joutoku H, Sakuragi M, Takehara M, Sakuma Y, Nishimura W, Fujii H, Yasuda Y. Comparison between the antiemetic effects of palonosetron and granisetron in breast cancer patients treated with anthracycline-based regimens. Oncol Lett 2015; 9: 119-124.
Nishimura W, Oishi H, Funahashi H, Fujiwara T, Takahashi S, Yasuda K. Generation and characterization of MafA-Kusabira Orange mice. Endocr J 2015; 62: 37-51.
Eto K, Nishimura W, Oishi H, Udagawa H, Kawaguchi M, Hiramoto M, Fujiwara T, Takahashi S, Yasuda K. MafA is required for postnatal proliferation of pancreatic β-cells. PLoS ONE 2014; 9: e104184.
Nishimura W, Eto K, Miki A, Goto M, Kawaguchi M, Nammo T, Udagawa H, Hiramoto M, Shimizu Y, Okamura T, Fujiwara T, Yasuda Y, Yasuda K. Quantitative assessment of Pdx1 promoter activity in vivo using a secreted luciferase reporter system. Endocrinology 2013; 154: 4388-4395.
Yokouchi H, Eto K, Nishimura W, Takeda N, Kaburagi Y, Yamamoto S, Yasuda K. Angiopoietin-like protein 4 (ANGPTL4) is induced by high glucose in retinal pigment epithelial cells and exhibits potent angiogenic activity on retinal endothelial cells. Acta Ophthalmol 2013; 91: e289-297.
Li WC, Rukstalis JM, Nishimura W, Tchipashvili V, Habener JF, Sharma A, Bonner-Weir S. Activation of pancreatic duct-derived progenitor cells during pancreas regeneration in adult rats. J Cell Sci 2010; 123: 2792-2802.
Vetere A, Li WC, Paroni F, Juhl K, Guo L, Nishimura W, Dai X, Bonner-Weir S, Sharma A. OVO Homolog-like 1 (OVOl1) Transcription factor: a Novel Target of Neurogenin-3 in pancreas. Diabetologia 2010; 53: 115-122.
Iwasa H, Yu S, Xue J, Driscoll M. Novel EGF pathway regulators modulate C. elegans healthspan and lifespan via EGF receptor, PLC-gamma, and IP3R activation. Aging Cell 2010; 9, 490-505.
Nishimura W, Bonner-Weir S, Sharma A. Expression of MafA in early pancreatic progenitors is detrimental to the development of pancreas. Dev Biol 2009; 333: 108-120.
Kondo T, Kahattabi IE, Nishimura W, Laybutt DR, Geraldes P, Shah S, King G, Bonner-Weir S, Weir G, Sharma A. p38 MAPK is a major regulator of MafA protein stability under oxidative stress. Mol Endocrinol 2009; 23: 1281-1290.
Jiang Y, Nishimura W, Devor-Henneman D, Kusewitt D, Wang H, Holloway MP, Dohi T, Sabo E, Robinson ML, Altieri DC, Sharma A, Altura RA. Postnatal expansion of the pancreatic β-cell mass is dependent on survivin. Diabetes 2008; 57: 2718-2727.
Nishimura W, Rowan S, Maas R, Bonner-Weir S, Sell SM, Sharma A. Preferential reduction of β-cells derived from Pax6-MafB pathway in MafB deficient mice. Dev Biol 2008; 314: 443-456.
Nishimura W, Kondo T, Salameh T, Kahattabi IE, Dodge R, Bonner-Weir S, Sharma A. A switch from MafB to MafA expression accompanies differentiation to pancreatic β-cells. Dev Biol 2006; 293: 526-539.
Nishimura W, Salameh T, Kondo T, Sharma A. Regulation of insulin gene expression by overlapping DNA-binding elements. Biochem J 2005; 392: 181-189.
